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Effects of human γ-globin in murine β-thalassaemia

Murine models of β-thalassaemia have been used to test therapeutic globin gene vectors. However, the level of γ-globin expression necessary to achieve full phenotypic correction in these models is unclear. In order to address this issue, we carried out breeding and transplantation studies in murine...

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Detalhes bibliográficos
Main Authors: Nishino, Tamon, Cao, Hua, Stamatoyannopoulos, George, Emery, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811697/
https://ncbi.nlm.nih.gov/pubmed/16803575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2006.06102.x
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