A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G(2)/M DNA Damage Checkpoint

DNA damage checkpoints arrest cell cycle progression to facilitate DNA repair. The ability to survive genotoxic insults depends not only on the initiation of cell cycle checkpoints but also on checkpoint maintenance. While activation of DNA damage checkpoints has been studied extensively, molecular...

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Bibliografiset tiedot
Päätekijät: van Vugt, Marcel A. T. M., Gardino, Alexandra K., Linding, Rune, Ostheimer, Gerard J., Reinhardt, H. Christian, Ong, Shao-En, Tan, Chris S., Miao, Hua, Keezer, Susan M., Li, Jeijin, Pawson, Tony, Lewis, Timothy A., Carr, Steven A., Smerdon, Stephen J., Brummelkamp, Thijn R., Yaffe, Michael B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2010
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811157/
https://ncbi.nlm.nih.gov/pubmed/20126263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000287
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