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Subtype Polymorphisms Among HIV-1 Protease Variants Confer Altered Flap Conformations and Flexibility
[Image: see text] Human immunodeficiency virus type 1 (HIV-1) protease plays a fundamental role in the maturation and life cycle of the retrovirus HIV-1, as it functions in regulating post-translational processing of the viral polyproteins gag and gag-pol; thus, is a key target of AIDS antiviral the...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2810526/ https://ncbi.nlm.nih.gov/pubmed/19788299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja907088a |
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