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Conformational Preferences of Substrates for Human Prolyl 4-Hydroxylase
Prolyl 4-hydroxylase (P4H) catalyzes the post-translational hydroxylation of (2S)-proline (Pro) residues in procollagen strands. The resulting (2S,4R)-4-hydroxyproline (Hyp) residues are essential for the folding, secretion, and stability of the collagen triple helix. Even though its product (Hyp) d...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2810141/ https://ncbi.nlm.nih.gov/pubmed/18702512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8009373 |
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