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Stringency of the 2-His–1-Asp Active-Site Motif in Prolyl 4-Hydroxylase
The non-heme iron(II) dioxygenase family of enzymes contain a common 2-His–1-carboxylate iron-binding motif. These enzymes catalyze a wide variety of oxidative reactions, such as the hydroxylation of aliphatic C–H bonds. Prolyl 4-hydroxylase (P4H) is an α-ketoglutarate-dependent iron(II) dioxygenase...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2767507/ https://ncbi.nlm.nih.gov/pubmed/19890397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007635 |
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