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Direct and continuous assay for prolyl 4-hydroxylase

Prolyl 4-hydroxylase (P4H) is a non-heme iron dioxygenase that catalyzes the post-translational hydroxylation of (2S)-proline (Pro) residues in protocollagen strands. The resulting (2S,4R)-4-hydroxyproline (Hyp) residues are essential for the folding, secretion, and stability of the collagen triple...

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Detalles Bibliográficos
Autores principales: Gorres, Kelly L., Raines, Ronald T.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643311/
https://ncbi.nlm.nih.gov/pubmed/19111518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2008.11.046
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