Human Recombinant ACE2 Reduces the Progression of Diabetic Nephropathy

OBJECTIVE: Diabetic nephropathy is one of the most common causes of end-stage renal failure. Inhibition of ACE2 function accelerates diabetic kidney injury, whereas renal ACE2 is downregulated in diabetic nephropathy. We examined the ability of human recombinant ACE2 (hrACE2) to slow the progression...

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Hauptverfasser: Oudit, Gavin Y., Liu, George C., Zhong, JiuChang, Basu, Ratnadeep, Chow, Fung L., Zhou, Joyce, Loibner, Hans, Janzek, Evelyne, Schuster, Manfred, Penninger, Josef M., Herzenberg, Andrew M., Kassiri, Zamaneh, Scholey, James W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2010
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809962/
https://ncbi.nlm.nih.gov/pubmed/19934006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1218
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