Human Recombinant ACE2 Reduces the Progression of Diabetic Nephropathy

OBJECTIVE: Diabetic nephropathy is one of the most common causes of end-stage renal failure. Inhibition of ACE2 function accelerates diabetic kidney injury, whereas renal ACE2 is downregulated in diabetic nephropathy. We examined the ability of human recombinant ACE2 (hrACE2) to slow the progression...

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Bibliographic Details
Main Authors:	Oudit, Gavin Y., Liu, George C., Zhong, JiuChang, Basu, Ratnadeep, Chow, Fung L., Zhou, Joyce, Loibner, Hans, Janzek, Evelyne, Schuster, Manfred, Penninger, Josef M., Herzenberg, Andrew M., Kassiri, Zamaneh, Scholey, James W.
Format:	Artigo
Language:	Inglês
Published:	American Diabetes Association 2010
Subjects:	Original Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2809962/ https://ncbi.nlm.nih.gov/pubmed/19934006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1218
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Human Recombinant ACE2 Reduces the Progression of Diabetic Nephropathy

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