Human Recombinant ACE2 Reduces the Progression of Diabetic Nephropathy

OBJECTIVE: Diabetic nephropathy is one of the most common causes of end-stage renal failure. Inhibition of ACE2 function accelerates diabetic kidney injury, whereas renal ACE2 is downregulated in diabetic nephropathy. We examined the ability of human recombinant ACE2 (hrACE2) to slow the progression...

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Autors principals: Oudit, Gavin Y., Liu, George C., Zhong, JiuChang, Basu, Ratnadeep, Chow, Fung L., Zhou, Joyce, Loibner, Hans, Janzek, Evelyne, Schuster, Manfred, Penninger, Josef M., Herzenberg, Andrew M., Kassiri, Zamaneh, Scholey, James W.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2010
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809962/
https://ncbi.nlm.nih.gov/pubmed/19934006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1218
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