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Protease-Sensitive Synthetic Prions
Prions arise when the cellular prion protein (PrP(C)) undergoes a self-propagating conformational change; the resulting infectious conformer is designated PrP(Sc). Frequently, PrP(Sc) is protease-resistant but protease-sensitive (s) prions have been isolated in humans and other animals. We report he...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2809756/ https://ncbi.nlm.nih.gov/pubmed/20107515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000736 |
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