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Specificity of Human Thymine DNA Glycosylase Depends on N-Glycosidic Bond Stability
Initiating the DNA base excision repair pathway, DNA glycosylases find and hydrolytically excise damaged bases from DNA. While some DNA glycosylases exhibit narrow specificity, others remove multiple forms of damage. Human thymine DNA glycosylase (hTDG) cleaves thymine from mutagenic G·T mispairs an...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2809119/ https://ncbi.nlm.nih.gov/pubmed/16984202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0634829 |
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