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Induction of human γ globin gene expression by histone deacetylase inhibitors

We investigated the induction of human γ globin gene activity by 3 classes of histone deacetylase inhibitors: amide analogues of trichostatin A, hydroxamic acid analogues of trapoxin, and scriptaid and its analogues. The screening consisted of measuring the effects of these compounds on γ and β huma...

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Bibliographic Details
Main Authors: Cao, Hua, Stamatoyannopoulos, George, Jung, Manfred
Format: Artigo
Language:Inglês
Published: 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808412/
https://ncbi.nlm.nih.gov/pubmed/12920038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2003-02-0478
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