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Nuclear-Cytoplasmic Shuttling of Chibby Controls β-Catenin Signaling
In the canonical Wnt pathway, β-catenin acts as a key coactivator that stimulates target gene expression through interaction with Tcf/Lef transcription factors. Its nuclear accumulation is the hallmark of active Wnt signaling and is frequently associated with cancers. Chibby (Cby) is an evolutionari...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Cell Biology
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2808236/ https://ncbi.nlm.nih.gov/pubmed/19940019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-05-0437 |
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