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Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of β-catenin
Wnt signaling regulates many aspects of development by increasing the signaling activity of β-catenin. Axin is a negative regulator of the Wnt signaling pathway, and it is responsible for the formation of the β-catenin degradation complex. Genetic studies with Drosophila suggest that Axin promotes c...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2004
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC365714/ https://ncbi.nlm.nih.gov/pubmed/14981260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307344101 |
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