Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of β-catenin
Wnt signaling regulates many aspects of development by increasing the signaling activity of β-catenin. Axin is a negative regulator of the Wnt signaling pathway, and it is responsible for the formation of the β-catenin degradation complex. Genetic studies with Drosophila suggest that Axin promotes c...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365714/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14981260/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307344101 |
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