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Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of β-catenin

Wnt signaling regulates many aspects of development by increasing the signaling activity of β-catenin. Axin is a negative regulator of the Wnt signaling pathway, and it is responsible for the formation of the β-catenin degradation complex. Genetic studies with Drosophila suggest that Axin promotes c...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Cong, Feng, Varmus, Harold
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2004
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365714/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14981260/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307344101
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