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Chibby Promotes Adipocyte Differentiation through Inhibition of β-Catenin Signaling

The canonical Wnt/β-catenin signaling pathway plays diverse roles in embryonic development and disease. Activation of this pathway, likely by Wnt-10b, has been shown to inhibit adipogenesis in cultured 3T3-L1 preadipocytes and in mice. Here, we report that the β-catenin antagonist Chibby (Cby) is re...

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Hlavní autoři: Li, Feng-Qian, Singh, Amar M., Mofunanya, Adaobi, Love, Damon, Terada, Naohiro, Moon, Randall T., Takemaru, Ken-Ichi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900052/
https://ncbi.nlm.nih.gov/pubmed/17403895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01640-06
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