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Nuclear-Cytoplasmic Shuttling of Chibby Controls β-Catenin Signaling

In the canonical Wnt pathway, β-catenin acts as a key coactivator that stimulates target gene expression through interaction with Tcf/Lef transcription factors. Its nuclear accumulation is the hallmark of active Wnt signaling and is frequently associated with cancers. Chibby (Cby) is an evolutionari...

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Bibliografiske detaljer
Main Authors: Li, Feng-Qian, Mofunanya, Adaobi, Fischer, Victoria, Hall, Jason, Takemaru, Ken-Ichi
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808236/
https://ncbi.nlm.nih.gov/pubmed/19940019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-05-0437
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