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Force-induced cleavage of single VWFA1A2A3 tridomains by ADAMTS-13
A disintegrin and metalloprotease with a thrombospondin type 1 motifs 13 (ADAMTS-13) regulates hemostasis by cleaving the folded A2 domain of von Willebrand factor (VWF). The cleavage is regulated by forces as it occurs in flowing blood. We tested the hypothesis that force-induced A2 domain unfoldin...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2808159/ https://ncbi.nlm.nih.gov/pubmed/19897584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-03-210369 |
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