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Domain-specific mechanical modulation of VWF–ADAMTS13 interaction
Hemodynamic forces activate the Von Willebrand factor (VWF) and facilitate its cleavage by a disintegrin and metalloprotease with thrombospondin motifs-13 (ADAMTS13), reducing the adhesive activity of VWF. Biochemical assays have mapped the binding sites on both molecules. However, these assays requ...
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| Publicado no: | Mol Biol Cell |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6727775/ https://ncbi.nlm.nih.gov/pubmed/31067148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-01-0021 |
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