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Differential roles for the inositol phosphatase SHIP in the regulation of macrophages and lymphocytes

The SH2 domain-containing inositol 5′-phosphatase (SHIP) negatively regulates antigen, cytokine, and Fc receptor signaling pathways in immune cells. Our knowledge of the function of SHIP largely derives from in vitro studies that utilized SHIP-deficient cell lines and immune cells isolated from SHIP...

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Autors principals: Leung, Wai-Hang, Tarasenko, Tatyana, Bolland, Silvia
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807985/
https://ncbi.nlm.nih.gov/pubmed/18989630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12026-008-8078-1
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