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Aberrant antibody affinity selection in SHIP-deficient B cells
The strength of the Ag receptor signal influences development and negative selection of B cells, and it might also affect B-cell survival and selection in the GC. Here, we have used mice with B-cell-specific deletion of the 5′-inositol phosphatase SHIP as a model to study affinity selection in cells...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3903325/ https://ncbi.nlm.nih.gov/pubmed/23135975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201242809 |
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