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T cell-specific deletion of the inositol phosphatase SHIP reveals its role in regulating Th1/Th2 and cytotoxic responses

The 5′-phosphoinositol phosphatase SHIP negatively regulates signaling pathways triggered by antigen, cytokine and Fc receptors in both lymphocytes and myeloid cells. Mice with germ-line (null) deletion of SHIP develop a myeloproliferative-like syndrome that causes early lethality. Lymphocyte anomal...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Tarasenko, Tatyana, Kole, Hemanta K., Chi, Anthony W., Mentink-Kane, Margaret M., Wynn, Thomas A., Bolland, Silvia
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040907/
https://ncbi.nlm.nih.gov/pubmed/17585010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704853104
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