T cell-specific deletion of the inositol phosphatase SHIP reveals its role in regulating Th1/Th2 and cytotoxic responses

The 5′-phosphoinositol phosphatase SHIP negatively regulates signaling pathways triggered by antigen, cytokine and Fc receptors in both lymphocytes and myeloid cells. Mice with germ-line (null) deletion of SHIP develop a myeloproliferative-like syndrome that causes early lethality. Lymphocyte anomal...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Tarasenko, Tatyana, Kole, Hemanta K., Chi, Anthony W., Mentink-Kane, Margaret M., Wynn, Thomas A., Bolland, Silvia
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2007
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040907/
https://ncbi.nlm.nih.gov/pubmed/17585010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704853104
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki