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Differential roles for the inositol phosphatase SHIP in the regulation of macrophages and lymphocytes
The SH2 domain-containing inositol 5′-phosphatase (SHIP) negatively regulates antigen, cytokine, and Fc receptor signaling pathways in immune cells. Our knowledge of the function of SHIP largely derives from in vitro studies that utilized SHIP-deficient cell lines and immune cells isolated from SHIP...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2807985/ https://ncbi.nlm.nih.gov/pubmed/18989630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12026-008-8078-1 |
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