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Protein kinase C α and ε phosphorylation of troponin and myosin binding protein C reduce Ca(2+) sensitivity in human myocardium
Previous studies indicated that the increase in protein kinase C (PKC)-mediated myofilament protein phosphorylation observed in failing myocardium might be detrimental for contractile function. This study was designed to reveal and compare the effects of PKCα- and PKCε-mediated phosphorylation on my...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
D. Steinkopff-Verlag
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2807945/ https://ncbi.nlm.nih.gov/pubmed/19655190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-009-0053-z |
| Oznake: |
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