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PKCα-Specific Phosphorylation of the Troponin Complex in Human Myocardium: A Functional and Proteomics Analysis

AIMS: Protein kinase Cα (PKCα) is one of the predominant PKC isoforms that phosphorylate cardiac troponin. PKCα is implicated in heart failure and serves as a potential therapeutic target, however, the exact consequences for contractile function in human myocardium are unclear. This study aimed to i...

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書誌詳細
主要な著者: Kooij, Viola, Zhang, Pingbo, Piersma, Sander R., Sequeira, Vasco, Boontje, Nicky M., Wijnker, Paul J. M., Jiménez, Connie R., Jaquet, Kornelia E., dos Remedios, Cris, Murphy, Anne M., Van Eyk, Jennifer E., van der Velden, Jolanda, Stienen, Ger JM.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792062/
https://ncbi.nlm.nih.gov/pubmed/24116014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074847
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