Frequency-dependent myofilament Ca(2+) desensitization in failing rat myocardium

The positive force–frequency relation, one of the key factors modulating performance of healthy myocardium, has been attributed to an increased Ca(2+) influx per unit of time. In failing hearts, a blunted, flat or negative force–frequency relation has been found. In healthy and failing hearts freque...

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Detalhes bibliográficos
Main Authors: Lamberts, Regis R, Hamdani, Nazha, Soekhoe, Tenoedj W, Boontje, Nicky M, Zaremba, Ruud, Walker, Lori A, de Tombe, Pieter P, van der Velden, Jolanda, Stienen, Ger J M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075316/
https://ncbi.nlm.nih.gov/pubmed/17478529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.134486
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