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Conservation of DNA-binding specificity and oligomerisation properties within the p53 family

BACKGROUND: Transcription factors activate their target genes by binding to specific response elements. Many transcription factor families evolved from a common ancestor by gene duplication and subsequent divergent evolution. Members of the p53 family, which play key roles in cell-cycle control and...

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Auteurs principaux: Brandt, Tobias, Petrovich, Miriana, Joerger, Andreas C, Veprintsev, Dmitry B
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807882/
https://ncbi.nlm.nih.gov/pubmed/20030809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-628
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