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Effects of CpG Methylation on Recognition of DNA by the Tumour Suppressor p53
Methylation of DNA is one of the mechanisms controlling the expression landscape of the genome. Its pattern is altered in cancer and often results in the hypermethylation of the promoter regions and abnormal expression of tumour suppressor genes. Methylation of CpG dinucleotides located in the bindi...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2666794/ https://ncbi.nlm.nih.gov/pubmed/19084536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.11.054 |
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