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Effects of CpG Methylation on Recognition of DNA by the Tumour Suppressor p53

Methylation of DNA is one of the mechanisms controlling the expression landscape of the genome. Its pattern is altered in cancer and often results in the hypermethylation of the promoter regions and abnormal expression of tumour suppressor genes. Methylation of CpG dinucleotides located in the bindi...

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Sonraí Bibleagrafaíochta
Main Authors: Petrovich, Miriana, Veprintsev, Dmitry B.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666794/
https://ncbi.nlm.nih.gov/pubmed/19084536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.11.054
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