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Down-regulation of 20-HETE Synthesis and Signaling Inhibits Renal Adenocarcinoma Cell Proliferation and Tumor Growth

BACKGROUND: We examined the ability of inhibitors of the synthesis or actions of 20-HETE, metabolite of arachidonic acid, to inhibit proliferation of human renal carcinoma cell lines. MATERIALS AND METHODS: 786-O and 769-P cells were exposed to either 10 μM HET0016 (selective inhibitor of 20-HETE sy...

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Autori principali: Alexanian, Anna, Rufanova, Victoriya A., Miller, Bradley, Flasch, Averia, Roman, Richard, Sorokin, Andrey
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807614/
https://ncbi.nlm.nih.gov/pubmed/19846914
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