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20-HETE Mediates Proliferation of Renal Epithelial Cells in Polycystic Kidney Disease

Polycystic kidney diseases are characterized by abnormal proliferation of renal epithelial cells. In this study, the role of 20-hydroxyeicosatetraenoic acid (20-HETE), an endogenous cytochrome P450 metabolite of arachidonic acid with mitogenic properties, was evaluated in cystic renal disease. Daily...

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Detalhes bibliográficos
Main Authors: Park, Frank, Sweeney, William E., Jia, Guangfu, Roman, Richard J., Avner, Ellis D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2551562/
https://ncbi.nlm.nih.gov/pubmed/18596124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007070771
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