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20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism

20-Hydroxyeicosatetraenoic acid (20-HETE) has been reported to promote mitogenicity in a variety of cell types, including renal epithelial cells. However, the signal transduction pathways activated by 20-HETE have not been fully defined. The present study evaluated the effects of 20-HETE and its mor...

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Detalhes bibliográficos
Main Authors: Akbulut, Talha, Regner, Kevin R., Roman, Richard J., Avner, Ellis D., Falck, John R., Park, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739708/
https://ncbi.nlm.nih.gov/pubmed/19570883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00146.2009
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