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20-HETE-mediated cytotoxicity and apoptosis in ischemic kidney epithelial cells

20-HETE, a metabolite of arachidonic acid, has been implicated as a mediator of free radical formation and tissue death following ischemia- reperfusion (IR) injury in the brain and heart. The present study examined the role of this pathway in a simulated IR renal injury model in vitro. Modified self...

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Detalhes bibliográficos
Main Authors: Nilakantan, Vani, Maenpaa, Cheryl, Jia, Guangfu, Roman, Richard J., Park, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633439/
https://ncbi.nlm.nih.gov/pubmed/18171997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00387.2007
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