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Tesevatinib ameliorates progression of polycystic kidney disease in rodent models of autosomal recessive polycystic kidney disease

AIM: To investigate the therapeutic potential of tesevatinib (TSV), a unique multi-kinase inhibitor currently in Phase II clinical trials for autosomal dominant polycystic kidney disease (ADPKD), in well-defined rodent models of autosomal recessive polycystic kidney disease (ARPKD). METHODS: We admi...

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Bibliografiske detaljer
Udgivet i:World J Nephrol
Main Authors: Sweeney, William E, Frost, Philip, Avner, Ellis D
Format: Artigo
Sprog:Inglês
Udgivet: Baishideng Publishing Group Inc 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500456/
https://ncbi.nlm.nih.gov/pubmed/28729967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5527/wjn.v6.i4.188
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