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Targeting 20-HETE producing enzymes in cancer – rationale, pharmacology, and clinical potential
Studies demonstrate that lipid mediator 20-Hydroxyeicosatetraenoic acid (20-HETE) synthesis and signaling are associated with the growth of cancer cells in vitro and in vivo. Stable 20-HETE agonists promote the proliferation of cancer cells, whereas selective inhibitors of the 20-HETE-producing enzy...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3615879/ https://ncbi.nlm.nih.gov/pubmed/23569388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S31586 |
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