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20-HETE-producing Enzymes Are Up-regulated in Human Cancers

BACKGROUND: 20-Hydroxyeicosatetraenoic acid (20-HETE), a metabolite of arachidonic acid (AA) produced by the CYP4A and CYP4F enzyme families has been reported to induce mitogenic and angiogenic responses both in vitro and in vivo, and inhibitors of this pathway reduced growth of brain and kidney tum...

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Detalhes bibliográficos
Main Authors: ALEXANIAN, ANNA, MILLER, BRADLEY, ROMAN, RICHARD J., SOROKIN, ANDREY
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601443/
https://ncbi.nlm.nih.gov/pubmed/22798501
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