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Elevated production of 20-HETE in the cerebral vasculature contributes to severity of ischemic stroke and oxidative stress in spontaneously hypertensive rats

Hypertension is a major risk factor for stroke, but the factors that contribute to the increased incidence and severity of ischemic stroke in hypertension remain to be determined. 20-hydroxyeicosatetraenoic acid (20-HETE) has been reported to be a potent constrictor of cerebral arteries, and inhibit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dunn, Kathryn M., Renic, Marija, Flasch, Averia K., Harder, David R., Falck, John, Roman, Richard J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614536/
https://ncbi.nlm.nih.gov/pubmed/18952718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00512.2008
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