SP-D counteracts GM-CSF-mediated increase of granuloma formation by alveolar macrophages in lysinuric protein intolerance

BACKGROUND: Pulmonary alveolar proteinosis (PAP) is a syndrome with multiple etiologies and is often deadly in lysinuric protein intolerance (LPI). At present, PAP is treated by whole lung lavage or with granulocyte/monocyte colony stimulating factor (GM-CSF); however, the effectiveness of GM-CSF in...

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Autori principali: Douda, David N, Farmakovski, Nicole, Dell, Sharon, Grasemann, Hartmut, Palaniyar, Nades
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807424/
https://ncbi.nlm.nih.gov/pubmed/20030831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-4-29
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