In Lysinuric Protein Intolerance system y(+)L activity is defective in monocytes and in GM-CSF-differentiated macrophages

BACKGROUND: In the recessive aminoaciduria Lysinuric Protein Intolerance (LPI), mutations of SLC7A7/y+LAT1 impair system y(+)L transport activity for cationic amino acids. A severe complication of LPI is a form of Pulmonary Alveolar Proteinosis (PAP), in which alveolar spaces are filled with lipopro...

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Detalhes bibliográficos
Main Authors: Barilli, Amelia, Rotoli, Bianca Maria, Visigalli, Rossana, Bussolati, Ovidio, Gazzola, Gian C, Kadija, Zamir, Rodi, Giuseppe, Mariani, Francesca, Ruzza, Maria Lorena, Luisetti, Maurizio, Dall'Asta, Valeria
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999609/
https://ncbi.nlm.nih.gov/pubmed/21110863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-5-32
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