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A Lipid Mediator Hepoxilin A3 Is a Natural Inducer of Neutrophil Extracellular Traps in Human Neutrophils

Pulmonary exacerbations in cystic fibrosis airways are accompanied by inflammation, neutrophilia, and mucous thickening. Cystic fibrosis sputum contains a large amount of uncleared DNA contributed by neutrophil extracellular trap (NET) formation from neutrophils. The exact mechanisms of the inductio...

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Detalhes bibliográficos
Main Authors: David N. Douda, Hartmut Grasemann, Cecil Pace-Asciak, Nades Palaniyar
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Limited 2015-01-01
Colecção:Mediators of Inflammation
Acesso em linha:http://dx.doi.org/10.1155/2015/520871
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