Загрузка...

N- and O-Glycans Modulate Galectin-1 Binding, CD45 Signaling, and T Cell Death

Galectin-1, a β-galactoside-binding protein highly expressed in the thymus, induces apoptosis of specific thymocyte subsets and activated T cells. Galectin-1 binds to N- and O-glycans on several glycoprotein receptors, including CD7, CD43, and CD45. Here we show that galectin-1 signaling through CD4...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Earl, Lesley A., Bi, Shuguang, Baum, Linda G.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807281/
https://ncbi.nlm.nih.gov/pubmed/19920154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.066191
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!