Galectin binding to cells and glycoproteins with genetically modified glycosylation reveals galectin–glycan specificities in a natural context

Galectins compose a protein family defined by a conserved sequence motif conferring affinity for β-galactose–containing glycans. Moreover, galectins gain higher affinity and fine-tune specificity by glycan interactions at sites adjacent to their β-galactoside–binding site, as revealed by extensive t...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Nielsen, Mathias Ingemann, Stegmayr, John, Grant, Oliver C., Yang, Zhang, Nilsson, Ulf J., Boos, Irene, Carlsson, Michael C., Woods, Robert J., Unverzagt, Carlo, Leffler, Hakon, Wandall, Hans H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2018
Fag:
Glycobiology and Extracellular Matrices
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6311502/
https://ncbi.nlm.nih.gov/pubmed/30385505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004636
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