Galectin-1, -2, and -3 Exhibit Differential Recognition of Sialylated Glycans and Blood Group Antigens

Human galectins have functionally divergent roles, although most of the members of the galectin family bind weakly to the simple disaccharide lactose (Galβ1-4Glc). To assess the specificity of galectin-glycan interactions in more detail, we explored the binding of several important galectins (Gal-1,...

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Autors principals: Stowell, Sean R., Arthur, Connie M., Mehta, Padmaja, Slanina, Kristen A., Blixt, Ola, Leffler, Hakon, Smith, David F., Cummings, Richard D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
Matèries:
Glycobiology and Extracellular Matrices
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442294/
https://ncbi.nlm.nih.gov/pubmed/18216021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709545200
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