Dimeric Galectin-8 Induces Phosphatidylserine Exposure in Leukocytes through Polylactosamine Recognition by the C-terminal Domain

Human galectins have distinct and overlapping biological roles in immunological homeostasis. However, the underlying differences among galectins in glycan binding specificity regulating these functions are unclear. Galectin-8 (Gal-8), a tandem repeat galectin, has two distinct carbohydrate recogniti...

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Bibliografiske detaljer
Main Authors: Stowell, Sean R., Arthur, Connie M., Slanina, Kristin A., Horton, John R., Smith, David F., Cummings, Richard D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Glycobiology and Extracellular Matrices
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2459286/
https://ncbi.nlm.nih.gov/pubmed/18456665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802495200
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