Ligand Reduces Galectin-1 Sensitivity to Oxidative Inactivation by Enhancing Dimer Formation

Galectin-1 (Gal-1) regulates leukocyte turnover by inducing the cell surface exposure of phosphatidylserine (PS), a ligand that targets cells for phagocytic removal, in the absence of apoptosis. Gal-1 monomer-dimer equilibrium appears to modulate Gal-1-induced PS exposure, although the mechanism und...

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Detalhes bibliográficos
Main Authors: Stowell, Sean R., Cho, Moonjae, Feasley, Christa L., Arthur, Connie M., Song, Xuezheng, Colucci, Jennifer K., Karmakar, Sougata, Mehta, Padmaja, Dias-Baruffi, Marcelo, McEver, Rodger P., Cummings, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643495/
https://ncbi.nlm.nih.gov/pubmed/19103599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808925200
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