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Galectin-1 signaling in leukocytes requires expression of complex-type N-glycans

Dimeric galectin-1 (dGal-1) is a homodimeric lectin with multiple proposed functions. Although dGal-1 binds to diverse glycans, it is unclear whether dGal-1 preferentially binds to specific subsets of glycans on cell surfaces to transmit signals. To explore this question, we selectively inhibited ma...

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Hlavní autoři: Karmakar, Sougata, Stowell, Sean R, Cummings, Richard D, McEver, Rodger P
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733774/
https://ncbi.nlm.nih.gov/pubmed/18633135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwn066
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