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Novel Fluorescent Glycan Microarray Strategy Reveals Ligands for Galectins

Galectin-1 (Gal-1) and galectin-3 (Gal-3) are widely expressed galectins with immunoregulatory functions in animals. To explore their glycan specificity, we developed microarrays of naturally occurring glycans using a novel bifunctional fluorescent linker, 2-amino-N-(2-aminoethyl)-benzamide (AEAB),...

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Detalhes bibliográficos
Main Authors: Song, Xuezheng, Xia, Baoyun, Stowell, Sean R., Lasanajak, Yi, Smith, David F., Cummings, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662446/
https://ncbi.nlm.nih.gov/pubmed/19171304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2008.11.004
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