Mutational Tuning of Galectin-3 Specificity and Biological Function

Galectins are defined by a conserved β-galactoside binding site that has been linked to many of their important functions in e.g. cell adhesion, signaling, and intracellular trafficking. Weak adjacent sites may enhance or decrease affinity for natural β-galactoside-containing glycoconjugates, but li...

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Bibliographische Detailangaben
Hauptverfasser: Salomonsson, Emma, Carlsson, Michael C., Osla, Veronica, Hendus-Altenburger, Ruth, Kahl-Knutson, Barbro, Öberg, Christopher T., Sundin, Anders, Nilsson, Rickard, Nordberg-Karlsson, Eva, Nilsson, Ulf J., Karlsson, Anna, Rini, James M., Leffler, Hakon
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Glycobiology and Extracellular Matrices
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966122/
https://ncbi.nlm.nih.gov/pubmed/20807768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.098160
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