Mutational Tuning of Galectin-3 Specificity and Biological Function

Galectins are defined by a conserved β-galactoside binding site that has been linked to many of their important functions in e.g. cell adhesion, signaling, and intracellular trafficking. Weak adjacent sites may enhance or decrease affinity for natural β-galactoside-containing glycoconjugates, but li...

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Detalles Bibliográficos
Main Authors: Salomonsson, Emma, Carlsson, Michael C., Osla, Veronica, Hendus-Altenburger, Ruth, Kahl-Knutson, Barbro, Öberg, Christopher T., Sundin, Anders, Nilsson, Rickard, Nordberg-Karlsson, Eva, Nilsson, Ulf J., Karlsson, Anna, Rini, James M., Leffler, Hakon
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Glycobiology and Extracellular Matrices
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966122/
https://ncbi.nlm.nih.gov/pubmed/20807768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.098160
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