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N- and O-Glycans Modulate Galectin-1 Binding, CD45 Signaling, and T Cell Death

Galectin-1, a β-galactoside-binding protein highly expressed in the thymus, induces apoptosis of specific thymocyte subsets and activated T cells. Galectin-1 binds to N- and O-glycans on several glycoprotein receptors, including CD7, CD43, and CD45. Here we show that galectin-1 signaling through CD4...

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書誌詳細
主要な著者: Earl, Lesley A., Bi, Shuguang, Baum, Linda G.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807281/
https://ncbi.nlm.nih.gov/pubmed/19920154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.066191
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